Senescence

Senescence is the last stage of life.

Translators are the sworn enemies of jokes; the exigencies of their deplorable trade cause them to maul the poor little things about while they are putting them into new clothes, and the result is death, or at the least an appearance of vacuous senescence; but jokes are only the crystallization of humour; it exists also in less tangible forms, such as style and all that collection of effects vaguely lumped together and called "atmosphere."

Organized shuffleboard has always filled me with dread. Everything about it suggests infirm senescence and death: it’s like it’s a game played on the skin of a void and the rasp of the sliding puck is the sound of that skin getting abraded away bit by bit.

Over the next 150 years the known age of the Earth expanded a millionfold and lost worlds of the past were found to have overflowed with species now gone. The chain stretched, aged, and eventually succumbed to senescence.

2018, University of Edinburgh, "Liver Study Offers Insights into Hard-to-treat Diseases" (9 March 2018), Drug Discovery & Development. Tests in mice found that inducing senescence in bile duct cells - mimicking the process seen in human bile duct disease - led to liver scarring and damage of liver function.