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If, on the other hand, a tumor consist chiefly of fibre or fibrillating blastema, the presumption of its cancerousness diminishes; we have, however, seen a growth in the liver, which had all the aspect of a scirrhous formation, and probably was so, which yet consisted solely of fibre-forming solid blastema.
Source: wiktionary
Only one line of mouse cells will perform this trick— a line called NIH 3T3 that has been bred in the laboratory for so many generations that it has long since forgotten what normality is, and is within a whisker of cancerousness even without the intervention of extraneous oncogenes.
Source: wiktionary
Starting in 1999, he began to mutate particular genes in human cells in culture and then to “interrogate” them for their cancerousness.
Source: wiktionary