Ranked by relevance and common usage.
Keep "epigenetic" when the sentence already sounds natural, when a synonym would add unintended emphasis, or when readers need the most familiar wording. A synonym should clarify or sharpen the message, not simply make the sentence look more varied.
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Choose a synonym only if it keeps the core idea of "epigenetic" intact in the sentence you are editing.
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Review note: Synonym lists are ranked with lexical data and reviewed for practical writing value. Use the comparison notes, sentence evidence, and source labels together; a high-ranking synonym can still be wrong when the audience, register, or grammar changes.
After choosing a replacement for "epigenetic", read the sentence once for meaning and once for rhythm. The best synonym should feel natural in the full sentence, not only accurate in a word list.
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4 total sentences available.
The old and optimistic “one gene — one character” concept has long been invalidated by phenomena such as pleiotropy and polygeny, and for a generation now we have thought of genomic activity as a system of complex epigenetic interactions — an epigenetic landscape.
Source: wiktionary
Every cell in the body contains the same DNA but epigenetic settings on cells in the bone and blood, for example, mean the tissues do very different jobs. The epigenetic consequences of a huge range of environmental factors are under investigation, from exposure to drugs, chemicals and hormones, to the impact of poor maternal care in infancy, and the likelihood that they are as hereditable as DNA.
Source: wiktionary
It is now possible to define whole epigenomes, representing the totality of epigenetic marks in a given cell type. Epigenetic processes are essential for packaging and interpreting the genome, are fundamental to normal development and are increasingly recognized as being involved in human disease.
Source: wiktionary
As one celebrated example, if you're a baby rat growing up with an atypically inattentive mother, epigenetic changes in the regulation of one gene in your hippocampus will make it harder for you to recover from stress as an adult.
Source: wiktionary
Closest matches include generative, genetic, genial, genital.
Compare the replacement against real sentence context. This entry includes sample sentences so you can check tone, grammar, and meaning before swapping words.