At that point of time the skin is macroscopically seen to be slightly thickened and is in course of transition to the pachydermal stage.
Source: wiktionary
Ranked by relevance and common usage.
Keep "pachydermal" when the sentence already sounds natural, when a synonym would add unintended emphasis, or when readers need the most familiar wording. A synonym should clarify or sharpen the message, not simply make the sentence look more varied.
If two options seem close, choose the one that best matches the audience and purpose of the sentence.
Choose a synonym only if it keeps the core idea of "pachydermal" intact in the sentence you are editing.
Check whether the replacement sounds more formal, casual, emotional, technical, or forceful than the original word.
Read the full sentence after the swap. Keep the synonym only when the sentence becomes clearer or more precise.
Review note: Synonym lists are ranked with lexical data and reviewed for practical writing value. Use the comparison notes, sentence evidence, and source labels together; a high-ranking synonym can still be wrong when the audience, register, or grammar changes.
After choosing a replacement for "pachydermal", read the sentence once for meaning and once for rhythm. The best synonym should feel natural in the full sentence, not only accurate in a word list.
If the synonym makes the sentence slower, vaguer, or more dramatic than intended, keep "pachydermal" or choose a simpler alternative from the closest-match group.
15 total sentences available.
At that point of time the skin is macroscopically seen to be slightly thickened and is in course of transition to the pachydermal stage.
Source: wiktionary
Periosteal changes occur in trauma, psoriatic arthritis (above ankle), HPOA, and pachydermal periostitis.
Source: wiktionary
In addition, the stooped posture progresses to the point where ribs rest on the iliac crest, and circumferential pachydermal skin folds develop at the pelvis and ribs.
Source: wiktionary
The anterior teeth are, however, displaced before the posterior ones are developed, although they have no vertical successors, which circumstance is also characteristic of the Elephant : the shape, the structure, and the mode of implantation of the molars of the Manatee quite accord with the pachydermal type, and herein more especially with the Dinotherium and Tapir.
Source: wiktionary
Showing 4 of 15 available sentences.
Closest matches include pachydermatous, pachydermic, pachydermous.
Compare the replacement against real sentence context. This entry includes sample sentences so you can check tone, grammar, and meaning before swapping words.