Pachydermy

If, as the inflammation recurs, the pachydermy spread beyond the point originally attacked, all the different grades of the disease are often exhibited simultaneously in the same extremity.

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Here in Edinburgh, whether on account of the pachydermy of its people or because the secretion is less virulent than it is elsewhere, cases of dermatitis caused by the plant are few.

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From the clinical point of view, there was striking, symmetrically expressed pachydermy of extremities, forehead, crown of the head and sometimes even the face with the symptom of cutis certicis gyrata.

Source: wiktionary

The haughty foreign secretary, to whom for the next fifty years all stories of aristocratic pachydermy were attached, was still to come.

Source: wiktionary