Benadryl

//ˈbɛnədɹɪl// noun

noun ·Rare ·Advanced level

Definitions

Noun
  1. 1
    An antihistamine medication used to stop allergies or as a sleep aid. countable, uncountable

    "The “Benadryl challenge”, wherein participants took a large amount of antihistamines in an attempt to produce hallucinogenic effects, led to at least one death."

  2. 2
    antihistamine (trade name Benadryl) used to treat allergic reactions involving the nasal passages (hay fever) and also to treat motion sickness wordnet

Synonyms

All synonyms
diphenhydramine

Example

More examples

"The “Benadryl challenge”, wherein participants took a large amount of antihistamines in an attempt to produce hallucinogenic effects, led to at least one death."

Etymology

Marketing name. From benzhydryl diethylaminoethyl ether.

More for "benadryl"

SynonymsSentencesPronunciationTranslate

Next best steps

Find stronger synonymsSee usage examplesCheck pronunciationBrowse writing guides

Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.