The “Benadryl challenge”, wherein participants took a large amount of antihistamines in an attempt to produce hallucinogenic effects, led to at least one death.
Source: wiktionary
Benadryl
//ˈbɛnədɹɪl//
Synonyms for "benadryl" (1 found)
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Noun(1 words)
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3 entriesSample sentences
4 total sentences available.
Reading his posts as posted, sitting in my NOBE studio, railing Benadryls, getting progressively less attractive to ex bae due to domestic overexposure, I was rapt.
Source: wiktionary
The Benadryl was for sleep, not allergies. I'd been having this thing where I woke up every night at two a.m.
Source: wiktionary
Benadryl, ZzzQuil and other drugs with diphenhydramine can also make you drowsy, since histamine helps the brain stay alert, said Dr. Zachary Rubin, an Illinois-based allergist and author of the upcoming book, “All About Allergies.”
Source: wiktionary
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Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.